Results and Publications
Scientific Articles
Output of APPROACH project in the form of scientific articles will be published on this page throughout the duration of the project.
Test–retest precision and longitudinal cartilage thickness loss in the IMI-APPROACH cohort
Authors: W. Wirth, S. Maschek, A.C.A. Marijnissen, A. Lalande, F.J. Blanco, F. Berenbaum, L.A. van de Stadt, M. Kloppenburg, I.K. Haugen, C.H. Ladel, J. Bacardit, A. Wisser, F. Eckstein, F.W. Roemer, F.P.J.G. Lafeber, H.H. Weinans, M. Jansen.
Available here.
Quantitative CT of the knee in the IMI-APPROACH osteoarthritis cohort: Association of bone mineral density with radiographic disease severity, meniscal coverage and meniscal extrusion
Authors: Rafael Heiss, Jean-Denis Laredo, Wolfgang Wirth, Mylène P. Jansen, Anne C.A. Marijnissen, Floris Lafeber, Agnes Lalande, Harrie H. Weinans, Francisco J. Blanco, Francis Berenbaum, Margreet Kloppenburg, Ida K. Haugen, Klaus Engelke, Frank W. Roemer.
Available here.
Exploring the differences between radiographic joint space width and MRI cartilage thickness changes using data from the IMI-APPROACH cohort
Authors: Jansen, M.P., Roemer, F.W., Marijnissen, A.K.C.A. et al.
Available here.
Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort
Authors: Frank W. Roemer, Mylène Jansen, Anne C. A. Marijnissen, Ali Guermazi, Rafael Heiss, Susanne Maschek, Agnes Lalande, Francisco J. Blanco, Francis Berenbaum, Lotte A. van de Stadt, Margreet Kloppenburg, Ida K. Haugen, Christoph H. Ladel, Jaume Bacardit, Anna Wisser, Felix Eckstein, Floris P. J. G. Lafeber, Harrie H. Weinans & Wolfgang Wirth.
Available here.
Test-retest precision and longitudinal cartilage thickness loss in the IMI-APPROACH cohort
Authors: Wolfgang Wirth, Susanne Maschek, Anne C.A. Marijnissen, Agnes Lalande, Francisco J. Blanco, Francis Berenbaum, Lotte A. van de Stadt, Margreet Kloppenburg, Ida K. Haugen, Christoph H. Ladel, Jaume Bacardit, Anna Wisser, Felix Eckstein, Frank W. Roemer, Floris P.J.G. Lafeber, Harrie H. Weinans, Mylène Jansen.
Available here.
The association of the lipid profile with knee and hand osteoarthritis severity: the IMI-APPROACH cohort
Authors: Loef M, van de Stadt L, Böhringer S, Bay-Jensen AC, Mobasheri A, Larkin J, Lafeber FPJG, Blanco FJ, Haugen IK, Berenbaum F, Giera M, Ioan-Facsinay A, Kloppenburg M.
Available here.
Predicted and actual 2-year structural and pain progression in the IMI-APPROACH knee osteoarthritis cohort
Authors: van Helvoort EM, Jansen MP, Marijnissen ACA, Kloppenburg M, Blanco FJ, Haugen IK, Berenbaum F, Bay-Jensen AC, Ladel C, Lalande A, Larkin J, Loughlin J, Mobasheri A, Weinans HH, Widera P, Bacardit J, Welsing PMJ, Lafeber FPJG.
Available here.
GaitSmart motion analysis compared to commonly used function outcome measures in the IMI-APPROACH knee osteoarthritis cohort
Authors: van Helvoort EM, Hodgins D, Mastbergen SC, Marijnissen ACA, Kloppenburg M, Blanco FJ, Haugen IK, Berenbaum F, Lafeber FPJG, Welsing PMJ.
Available here.
Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping
Authors: van Helvoort EM, Welsing PMJ, Jansen MP, Gielis WP, Loef M, Kloppenburg M, Blanco F, Haugen IK, Berenbaum F, Bay-Jensen AC, Ladel C, Lalande A, Larkin J, Loughlin J, Mobasheri A, Weinans H, Lafeber F, Eijkelkamp N, Mastbergen S.
Available here.
Osteoarthritis endotype discovery via clustering of biochemical marker data
Authors: Federico Angelini, Paweł Widera, Ali Mobasheri, Joseph Blair, André Struglics, Melanie Uebelhoer, Yves Henrotin, Anne CA Marijnissen, Margreet Kloppenburg, Francisco J Blanco, Ida K Haugen, Francis Berenbaum, Christoph Ladel, Jonathan Larkin, Anne C Bay-Jensen, Jaume Bacardit
Available here.
Baseline clinical characteristics of predicted structural and pain progressors in the IMI-APPROACH knee OA cohort
Authors: Eefje Martine van Helvoort, Christoph Ladel, Simon Mastbergen, Margreet Kloppenburg, Francisco J Blanco, Ida K Haugen, Francis Berenbaum, Jaume Bacardit, Pawel Widera, Paco M J Welsing and Floris Lafeber.
Available here.
Making the patient voice heard in a research consortium: experiences from an EU project (IMI-APPROACH)
Authors: Jane Taylor, Sjouke Dekker, Diny Jurg, Jon Skandsen, Maureen Grossman, Anne-Karien Marijnissen, Christoph Ladel, Ali Mobasheri, Jon Larkin, Harrie Weinans, Irene Kanter-Schlifke on behalf of the APPROACH research consortium.
Available here.
Relationship between motion, using the GaitSmartTM system, and radiographic knee osteoarthritis: an explorative analysis in the IMI-APPROACH cohort
Authors: Eefje M van Helvoort, Diana Hodgins, Simon C Mastbergen, Anne Karien Marijnissen, Hans Guehring, Marieke Loef, Margreet Kloppenburg, Francisco Blanco, Ida K Haugen, Francis Berenbaum, Floris P J G Lafeber, Paco M J Welsing
Available here.
Cohort profile: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predict phenotypes of osteoarthritis using clinical, imaging and biochemical markers
Authors: Eefje M van Helvoort, Willem E van Spil, Mylène P Jansen, Paco M J Welsing, Margreet Kloppenburg, Marieke Loef, Francisco J Blanco, Ida K Haugen, Francis Berenbaum, Jaume Bacardit, Christoph H Ladel, John Loughlin, Anne C Bay-Jensen, Ali Mobasheri, Jonathan Larkin, Janneke Boere, Harrie H Weinans, Agnes Lalande, Anne C A Marijnissen, Floris P J G Lafeber
Available here.
Multi-classifier prediction of knee osteoarthritis progression from incomplete imbalanced longitudinal data
Authors: Paweł Widera, Paco M. J. Welsing, Christoph Ladel, John Loughlin, Floris P.J.G. Lafeber, Florence Petit Dop, Jonathan Larkin, Harrie Weinans, Ali Mobasheri & Jaume Bacardit
Available here.